Ankylosing Spondylitis Research
Essential Reading
Here is a list of ‘must read’ papers that relate the potential impact of diet to help manage this condition. I’ve tried to highlight, where possible, some of the more interesting (and actionable) findings.
Treating Ankylosing Spondylitis with a Low or No Starch Diet
Report Title: “The Use of a Low Starch Diet in the Treatment of Patients Suffering from Ankylosing Spondylitis”
The Role of 'Leaky Gut' in Autoimmune Diseases
Report Title: “Leaky Gut and Autoimmunity: An Intricate Balance in Individuals Health and the Diseased State”
17 Years: The Slow Journey from Scientific Discovery to Treatment
Report Title: “The answer is 17 years, what is the question: understanding time lags in translational research”
The Klebsiella Bacteria and Ankylosing Spondylitis Connection
Report Title: “The Association of HLA-B27 and Klebsiella Pneumoniae in Ankylosing Spondylitis: A Systematic Review”
Sugar, Inflammation and Autoimmune Diseases
Report Title: “The Glucose Transporter GLUT3 Controls T Helper 17 Cell Responses Through Glycolytic-epigenetic Reprogramming”
New Study - The Low Starch Diet as an AS Treatment! Awaiting Results...
Report Title: “Effect of a Low Starch Diet in Patients With Ankylosing Spondylitis”
Looking for a specific study? Search here:
✅ Practical Steps
Below are some relevant studies which specifically cover inflammation, gut function and autoimmune disease. They cover simple, practical steps you can take to stay healthy with your diet and day to day life:
More Studies
Here is the full list of studies I’ve referenced on this website along with synopses where possible.
As well as ankylosing spondylitis specific studies, I’ve also included relevant studies on autoimmune disorders in general, rheumatoid arthritis and anything to do with gut permeability (‘leaky gut’) or inflammation
Number of Studies
Study: Improving Research into the Microbiome By Looking at How Long it Takes Food to Pass Through the Gut
Title of Study: "Advancing human gut microbiota research by considering gut transit time" Published: 28th September, 2022 | Link: View study here | Authors: Nicola Procházková, Gwen Falony, Lars Ove Dragsted, Tine Rask Licht, Jeroen Raes, and Henrik M Roager...
Study: How Sugar Upsets the Balance of Bacteria in Your Gut, Can Weaken Your Immune System and Increase Risk of ‘Metabolic Syndrome’
Title of Study: "Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome" Published: 29th August, 2022 | Authors: Yoshinaga Kawano, Madeline Edwards, Yiming Huang, Daniel Mucida, Kenya Honda, Ivaylo I. Ivanov | 🔗 View...
The Glucose Transporter GLUT3 Controls T Helper 17 Cell Responses Through Glycolytic-epigenetic Reprogramming (Sugar and Inflammation)
Published: March 21, 2022Authors: Sophia M. Hochrein, Hao Wu, Miriam Eckstein, Jan Van den Bossche, E. Dale Abel, Martin Vaeth In Summary: Sugar causes significant inflammation Eating excess sugar and other carbohydrates, over time, could lead to the development...
HLA-B27 and its Subtypes in World Populations
M. Khan Published: 1st July 1995 Abstract: "Twenty-five years ago, HLA-B27 was recognized as a new HLA specificity. It is present throughout Eurasia but is virtually absent among the genetically unmixed native populations of South America, the Bantus and Sans...
Consumption of Olive Oil and Risk of Total and Cause-Specific Mortality Among U.S. Adults
MartaGuasch-Ferré PhD, Yanping Li PhD, Walter C, Willett MD, Dr PH, Qi Sun MD, ScD Laura Sampson RD, Jordi Salas-Salvadó MD, Miguel A. Martínez-González MD, Meir J. Stampfer MD, Dr PH, Frank B. HuMD, PhD Published: January 2022 Background: "Olive oil consumption has...
Association between Klebsiella pneumoniae and ankylosing spondylitis: A systematic review and meta-analysis
Published: 12th January, 2022Authors: Fayu Long, Taiping Wang, Qing Li, Yiquan Xiong, Yong Zeng In Summary: 25 case-control studies showed "a significantly higher positive rate" of Klebsiella in patients with ankylosing spondylitisThese findings suggest Klebsiella...
Impact of Age on Mortality and Complications in Patients with Ankylosing Spondylitis Spine Fractures
Mayur Sharma, Nikhil Jain, Dengzhi Wang, Beatrice Ugiliweneza, Maxwell Boakye, Doniel Drazin Department of Neurosurgery, University of Louisville, 200 Abraham Flexner Hwy, Louisville, KY 40202, USA, Kentucky Spinal Cord Injury Research Center, School of Medicine,...
Comparison of the Antibacterial Activity of Australian Terminalia spp. Extracts Against Klebsiella Pneumoniae: A Potential Treatment for Ankylosing Spondylitis
Reece Courtney and Ian Edwin Cock Published: 16th December 2021 Abstract: "Traditional medicines prepared using Terminalia species have been used globally to treat inflammation and pathogenic infections. Recent studies have demonstrated that multiple Asian and African...
Efficacy and Safety of Fengshi Gutong Capsule in Patients with Active Ankylosing Spondylitis: A 4-week Randomized Controlled, Double-Blinded, Double-Dummy Trial
Ya Xi, Liudan Tua, Yanli Zhang, Qinghong Yu, Henglian Wu, Shanhui Ye, Haibo Li, Zena Chen, Jialing Wu, Shuangyan Cao, Qiujing Wei, Jieruo Gu Published: 8th October 2021 Abstract: "Fengshi Gutong Capsule (FSGTC) is a traditional Chinese herbal medicine that is composed...
Effect of a Low Starch Diet in Patients With Ankylosing Spondylitis
Published: 2021 - OngoingAuthors: Universidade do Porto, Portuguese Institute of Rheumatology, Centro de Investigação Interdisciplinar Egas Moniz In Summary: BREAKING NEWS: The first major clinical study of the effect of a Low Starch Diet on ankylosing...
A Pilot Study of Possible Anti-Inflammatory Effects of the Specific Carbohydrate Diet in Children with Juvenile Idiopathic Arthritis
Lillemor Berntson Published: 10 June 2021 Abstract: "To explore possible anti-inflammatory effects of the specific carbohydrate diet in children with juvenile idiopathic arthritis. This diet has shown anti-inflammatory effect in children with inflammatory bowel...
Gut Microbiota–MicroRNA Interactions in Ankylosing Spondylitis
Fataneh Tavasolian, Robert D. Inmanabc Spondylitis Program, Division of Rheumatology, Schroeder Arthritis Institute, University Health Network, Toronto, Ontario, Canada Krembil Research Institute, University Health Network, Toronto, Ontario, Canada Departments of...
Inflammasome Activation in Ankylosing Spondylitis is Associated with Gut Dysbiosis
Giuliana Guggino, Daniele Mauro, Aroldo Rizzo, Riccardo Alessandro, Stefania Raimondo, Anne-Sophie Bergot, M. Arifur Rahman, Jonathan J. Ellis, Simon Milling, Rik Lories, Dirk Elewaut, Matthew A. Brown, Ranjeny Thomas, Francesco Ciccia Published: 16th January 2021...
Comparison of Clinical Features in HLA-B27 Positive and Negative Patients With Axial Spondyloarthritis: Results From a Cohort of 4,131 Patients
Shangzhu Zhang, Yanhong Wang, Linyi Peng, Jinmei Su, Xiaofeng Zeng, Mengtao Li, Zhenbiao Wu, Jian Xu, Min Yang, Lijun Wu, Cheng Zhao, Xinwang Duan, Qin Li, Jing Zhu and Wenqiang Fan Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education,...
Leaky Gut and Autoimmunity: An Intricate Balance in Individuals Health and the Diseased State
Bilal Ahmad Paray, Mohammed Fahad Albeshr, Arif Tasleem Jan, and Irfan A. Rather Published 21st December 2020 Abstract: "Damage to the tissue and the ruining of functions characterize autoimmune syndromes. This review centers around leaky gut syndromes and how they...
Ocular Demodex: A Systematic Review of the Clinical Literature
Alexis Ceecee Zhang, Alex Muntz, Michael T M Wang, Jennifer P Craig and Laura E Downie Published: July 2020 Abstract: "There is increasing clinical and research interest in the potential contribution of Demodex to ocular surface disease. The aim of this systematic...
Study: People With Ankylosing Spondylitis Are More Likely to Experience Depression and Anxiety
Title of Study: "The incidence of depression and anxiety in patients with ankylosing spondylitis: a systematic review and meta-analysis" Published: 2nd March, 2020 | Link: View study here | Authors:Jamie YE. Park, Alyssa M. Howren, Enav Z. Zusman, John M....
An Add-On Training Program Involving Breathing Exercises, Cold Exposure, and Meditation Attenuates Inflammation and Disease Activity in Axial Spondyloarthritis – A Proof of Concept Trial
G. A. Buijze, H. M. Y. De Jong, M. Kox, M. G. van de Sande, D. Van Schaardenburg, R. M. Van Vugt, C. D. Popa, P. Pickkers, D. L. P. Baeten Published: December 2019 Objectives: "The primary objective of this trial was to assess safety and anti-inflammatory effects of...
The Microbiome in Autoimmune Diseases
Published: December 2018Authors: F. De Luca, and Y. Shoenfeld In Summary: Microbiota (such as bacteria in the gut) live symbiotically with humans which is why "the human microbiome might be a major player in autoimmunity"Dysbiosis can "induce autoimmune disease" for...
Importance of maintaining a low omega–6/omega–3 ratio for reducing inflammation
Published: 13th January, 2018Authors: James J DiNicolantonio and James H O’Keefe In Summary: Seed oils are high in omega 6 and can contribute to inflammation Marine omega 3s (fish oil) activate "anti inflammatory mechanisms"Decreasing our omega-6 / omega 3 ratio can...
Dietary practices and inflammatory bowel disease
Technical details from the study Abstract: "The etiology of inflammatory bowel disease (IBD) remains elusive but it is believed to result from incompletely understood interactions between environmental triggers in a potentially genetically susceptible host and a...